Margaret R. Larson Professor of Internal Medicine & Infectious Diseases and Chair, Department of Pharmacology & Experimental Neuroscience, College of Medicine
Director, Center for Neurodegenerative Disorders
Howard E. Gendelman, MD, unraveled how functional alterations in brain immunity induce metabolic changes and ultimately leads to neural cell damage for a broad range of infectious, metabolic, and neurodegenerative disorders. These discoveries have informed the development of therapeutics aimed at preventing, slowing, or reversing these conditions. Additionally, Dr. Gendleman has demonstrated that AIDS dementia is reversible, a finding realized at UNMC. His work has led to treatment strategies for Parkinson’s and viral diseases being tested in early clinical trials.
Dr. Gendelman has trained more than forty scientists (students and postdoctoral fellows) who have themselves developed independent successful careers in academia and industry. His leadership is credited with the growth of the Department of Pharmacology and Experimental Neuroscience at UNMC to be amongst the top-like ranked and federally funded departments (top ten) nationwide.